Publications

  1. Niazi F, Valadkhan S. (2012) "Computational analysis of functional long noncoding RNAs reveals lack of peptide-coding capacity and parallels with 3 ′ UTRs" RNA 18: 825-843. View PDF. Leave a question/comment. Cited 1 time as of 8/7/2012
  2. Valadkhan S. (2011) A SnRNP's Ordered Path to Maturity. Genes & Development 25.15 : 1563-567. View PDF. Leave a question/comment
  3. Jaladat Y, Zhang B, Mohammadi A, Valadkhan, S. (2011) Splicing of an intervening sequence by protein-free human snRNAs. RNA Biology 8:3. View PDF. Leave a question/comment.
  4. Lee C, Jaladat Y, Mohammadi A, Sharifi A, Geisler S, Valadkhan S. (2010) Metal Binding and Substrate Positioning by Evolutionarily Invariant U6 Sequences in Catalytically Active Protein-free SnRNAs. Rna 16.11:2226-238. View PDF. Leave a question/comment. Cited 4 times as of 8/7/2012.
  5. Jaladat Y, Valadkhan S. (2010) The spliceosomal proteome: At the heart of the largest cellular ribonucleoprotein machine. Proteomics 10:4128-4141. View PDF. Leave a question/comment. Cited 14 times as of 8/7/2012.
  6. Valadkhan S. (2010) Role of the SnRNAs in Spliceosomal Active Site. RNA Biology 7.3: 345-53. View PDF. Leave a question/comment. Cited 9 times as of 2010.
  7. Valadkhan S, Nilsen TW. (2010) Reprogramming of the non-coding transcriptome during brain development J.Biol. View PDF. Leave a question/comment. Cited 4 times as of 8/7/2012.
  8. Valadkhan S, Mohammadi A, Jaladat Y, Geisler S. (2009) Protein-free small nuclear RNAs catalyze a two-step splicing reaction. Proc Natl Acad Sci U S A. 106: 11901-11906. and supplementary data. View PDF. Leave a question/comment. Cited 21 times as of 8/7/2012.
  9. Valadkhan S., Manley JL. (2009) The use of simple model systems to study spliceosomal catalysis.RNA.15:4-7. View PDF. Leave a question/comment. Cited 3 times as of 8/7/2012.
  10. Valadkhan S., Mohammadi A., Wachtel C., Manley J.L. (2007) Protein-free spliceosomal snRNAs catalyze a reaction that resembles the first step of splicing. RNA. 13:2300-11. View PDF. Leave a question/comment. Cited 21 times as of 8/7/2012.
  11. Valadkhan S. (2007) The spliceosome: caught in a web of shifting interactions. Curr. Opin. Struct. Biol.17:310-5. View PDF. Leave a question/comment. Cited 27 times as of 8/7/2012.
  12. Valadkhan S. (2007) The spliceosome: a ribozyme at heart? Biol. Chem. 388:693-697. View PDF. Leave a question/comment. Cited 29 times as of 8/7/2012.
  13. Valadkhan S. (2005) snRNAs as the catalysts of pre-mRNA splicing. Curr. Opin. Chem. Biol. 9:603-608. View PDF. Leave a question/comment. Cited 53 times as of 8/7/2012.
  14. Valadkhan S. (2005) Young Scientist Award essay winner. Construction of a minimal, protein-free spliceosome. Science 307:863-864. View PDF. Leave a question/comment. Cited 2 times as of 8/7/2012.
  15. Valadkhan S., Manley JL. (2003) Characterization of the catalytic activity of U2 and U6 snRNAs. RNA 9:892-904. View PDF. Leave a question/comment. Cited 52 times as of 8/7/2012.
  16. Valadkhan S., Manley JL. (2002) Intrinsic metal binding by a spliceosomal RNA. Nat. Struct. Biol. 9:498-499. View PDF. Leave a question/comment. Cited 19 times as of 8/7/2012.
  17. Valadkhan S., Manley JL. (2001) Splicing-related catalysis by protein-free snRNAs. Nature 413:701-707. View PDF. Leave a question/comment. Cited 143 times as of 8/7/2012.
  18. Valadkhan S., Manley JL. (2000) A tertiary interaction detected in a human U2-U6 snRNA complex assembled in vitro resembles a genetically proven interaction in yeast. RNA 6:206-219. View PDF. Leave a question/comment. Cited 37 times as of 8/7/2012.
  19. Sun JS, Valadkhan S., Manley JL. (1998) A UV-crosslinkable interaction in human U6 snRNA. RNA 4:489-497. View PDF. Leave a question/comment. Cited 7 times as of 8/7/2012.